Balasubramanian, R and Maitra, Uday (2001) Design and Synthesis of Novel Chiral Dendritic Species Derived from Bile Acids. In: Journal Organic Chemistry, 66 (9). pp. 3035-3040.
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Bile acids have been used for the first time as the building block for the construction of dendritic units. Orthogonally functionalized 7-deoxycholic and cholic acid derivatives were synthesized. The construction of a bile acid heptamer, a nonamer, and a decamer using the convergent strategy are described in detail. Chromatographic, spectral, and optical properties of these molecules have been investigated. Molecular modeling suggests that these molecules have globular shapes with nanometric dimensions.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to American Chemical Society.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||16 Apr 2007|
|Last Modified:||19 Sep 2010 04:37|
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