Ganesh, Vijaya N and Jayaraman, N (2007) Synthesis of Septanosides through an Oxyglycal Route. In: Journal of Organic Chemistry, 72 (15). pp. 5500-5504.
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A new route to synthesize septanoside derivatives from protected 2-hydroxyglycals is reported. Ring expansion of a pyranoside to a septanoside was achieved through key reactions of a cyclopropanation, ring opening, oxidation, and reduction. Methyl septanoside derivatives, namely, methyl \alpha-D-glycero-Dtalo- septanoside and methyl \alpha-D-glycero-L-altro-septanoside, were synthesized in an overall yield of 35% and 46%, respectively, from the corresponding protected 2-hydroxy glycals.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to American Chemical Society(ACS).|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||11 Oct 2007|
|Last Modified:||19 Sep 2010 04:39|
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