ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Propargyloxycarbonyl (Poc) as a protective group for the hydroxyl function in carbohydrate synthesis

Sridhar, Perali Ramu and Chandrasekaran, S (2002) Propargyloxycarbonyl (Poc) as a protective group for the hydroxyl function in carbohydrate synthesis. In: Organic Letters, 26 (4). pp. 4731-4733.

[img] PDF
Propargyloxycarbonyl.pdf
Restricted to Registered users only

Download (70Kb) | Request a copy

Abstract

The propargyloxycarbonyl (Poc) group can be used for the selective protection of the hydroxyl function in carbohydrates and can be removed under neutral conditions using tetrathiomolybdate $MoS_4 \hspace{1mm}^{2-} (1)$ in $CH_3CN$ at room temperature. Under the conditions of deprotection benzylidine acetals, benzyl ethers, acetyl and levulinoyl esters, and allyl and benzyl carbonates are left untouched. It has also been shown that the new protective group (Poc) is compatible with acidic, basic, and also glycosylation conditions.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to American Chemical Society.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 12 Oct 2007
Last Modified: 19 Sep 2010 04:40
URI: http://eprints.iisc.ernet.in/id/eprint/12110

Actions (login required)

View Item View Item