Kant, Shashi and Bagaria, Ashima and Ramakumar, S (2002) Putative homeodomain proteins identified in prokaryotes based on pattern and sequence similarity. In: Biochemical and Biophysical Research Communications, 299 (2). pp. 229-232.
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A putative homeodomain has been identified in eubacterial genomes, which include several pathogens. The domain is related in sequence to homeodomain, a component specific to transcription factors and playing a very important role in eukaryotes such as controlling the developmental processes of the organism. The putative homeodomain has been characterized utilizing the eukaryotic homeodomain protein sequence signature present in PROSITE as well as the sequence similarity search using BLAST suite for different eubacterial genomes. These findings provide evidence for the occurrence of DNA-binding motif in prokarya similar to that in eukarya.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier.|
|Keywords:||Transcription factors;Homeodomain;Sequence pattern;Homeobox;DNA-binding domain;Prokaryote;Eukaryote;Pro-homeodomain|
|Department/Centre:||Division of Information Sciences > BioInformatics Centre
Division of Physical & Mathematical Sciences > Physics
|Date Deposited:||11 Oct 2007|
|Last Modified:||19 Sep 2010 04:40|
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