Bhattacharya, Santanu and Thomas, Mini (2001) Novel distamycin analogues: facile synthesis of cholesterol conjugates of distamycin-like oligopeptides. In: Tetrahedron Letters, 42 (20). pp. 3499-3502.
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A facile route towards the synthesis of the first examples of cholesterol-conjugated distamycin analogues is described. These compounds retain their strong binding capacity to double-stranded (ds)-DNA. Aqueous suspensions of these analogues exhibited closed, vesicle-like structures under transmission electron microscope.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||15 Oct 2007|
|Last Modified:||19 Sep 2010 04:40|
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