Sasisekharan, V and Bansal, M (1990) Self-similarity and the assembly of collagen molecules. In: Current Science, 59 (17-18). pp. 863-866.
The Bragg reflections seen on the equator, in the X-ray pattern of collagen fibrils, have been generally interpreted as arising from a quasi-hexagonal packing of the triplehelical collagen molecules. However, these reflections can be 'accurately' indexed only on the basis of a much larger monoclinic cell. In this paper 'we outline a completely different approach, based on the principle of self-similarity, to describe the assembly of rod-like molecules of collagen. Assuming that the collagen molecules are packed, with local exagonal site symmetry, but no long range translational order, an aperiodic lattice arrangement is described (with only the inter-molecular separation as a variable parameter). This can account for the observed equatorial X-ray pattern as well as the longer range lateral spacings seen. in collagen fibrils under the electron microscope.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Indian Academy of Sciences|
|Keywords:||collagen molecules;monoclinic cell;collagen fibrils|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit|
|Date Deposited:||01 Jan 2008|
|Last Modified:||19 Sep 2010 04:41|
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