Easwaran, KRK and Balasubramanian, SV (1990) Spectroscopic studies on the structure and aggregation of calcium ionophore, A23187. In: 5th Proceedings UNESCO International Conference, 1989.Full text not available from this repository.
Studies on the structure of calcium ionophore, A23187, using IR, UV, CD, fluorescence and NMR methods indicated that this ionophore forms a dimer in nonpolar solvents such as chloroform. When incorporated into a phospholipid vesicle, the spectra showed remarkable time dependent changes indicating further aggregation of the dimer into a stacked dimeric structure in dipalmitoylphosphatidylcholine vesicle. Results point to the possibility of A23187 transporting divalent cations across membranes by a pore rather than by a diffusive carrier model.
|Item Type:||Conference Proceedings|
|Additional Information:||Copyright of this article belongs to Birkhaeuser.|
|Keywords:||Spectroscopic studies;calcium ionophore;fluorescence;NMR methods|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit|
|Date Deposited:||28 Dec 2007|
|Last Modified:||08 Feb 2012 07:24|
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