Kumar, Madan A and Nayak, R (1990) A spectrophotometric method for detection of $5^\prime$-fluorouracil in plasma. In: Biochemical and Biophysical Research Communications, 169 (3). pp. 1153-1157.
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A quantitative method using spectrophotometry was devised for the detection of $5^\prime$-Fluorouracil(FUra) in plasma. Plasma samples obtained at different time intervals from drug treated rabbits were deproteinised using phenol. The aqueous phase was lyophilised and dissolved in 0.01 N NaOH and absorption was monitored at 305 nm. Levels of FUra in the plasma were calculated by comparing with a standard graph generated from known concentrations of FUra. As low as 1 $\mu$g of the drug per ml of plasma could be detected by this method.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Academic Press, Inc.|
|Department/Centre:||Division of Biological Sciences > Microbiology & Cell Biology|
|Date Deposited:||20 Feb 2008|
|Last Modified:||19 Sep 2010 04:41|
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