Krishnan, VV and Murali, N and Kumar, Anil (1989) A diffusion equation approach to spin diffusion in biomolecules. In: Journal of Magnetic Resonance, 84 (2). pp. 255-267.
Restricted to Registered users only
Download (0b) | Request a copy
A theoretical description of $1^H-1^H$ dipolar nuclear spin relaxation in a multispin system has been worked out by forming a diffusion equation for a one-dimensional chain of equidistant spins. The spin-diffusion equation is formed from first principles by assuming nearest neighbor interactions for a molecule undergoing isotropic random reorientation. This equation describes diffusion only in the long correlation limit (for $(\omega \tau_c > 1.118)$ and is solved for driven NOE experiments, for spins in a chain of infinite length $(0 <x< \infty)$, or for spins in a chain of finite length $(0 <x< L$). The solutions are obtained using the method of the Laplace transform for specified initial and boundary conditions. The observed selectivity of the NOE transfer in driven NOE experiments on a biomolecule which has a correlation factor $\omega\tau_c \sim3$ is indeed in conformity with the predictions obtained from the spin-diffusion equation.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier Science|
|Department/Centre:||Division of Chemical Sciences > Sophisticated Instruments Facility
Division of Physical & Mathematical Sciences > Physics
|Date Deposited:||14 Feb 2008|
|Last Modified:||19 Sep 2010 04:42|
Actions (login required)