Devajyothi, C and Brahmachari, Vani (1989) Modulation of DNA methyltransferase during the life cycle of a mealybug Planococcus lilacinus. In: FEBS Letters, 250 (2). pp. 134-138.
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The levels of de novo DNA methyltransferase were studied during the development of a mealybug, Planococcus lilacinus. No enzyme activity could be detected in extracts from second instar females. But the enzyme occurs at high levels in third instar females and is maintained at that level during fourth instar when gametogenesis, fertilization and chromosome imprinting occur. These results suggest a developmental stage-specific modulation of levels of DNA methyltransferase. Assays with synthetic polymers showed that the enzyme can methylate not only polymers containing GpG but also those containing CpA and CpI.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Federation of European Biochemical Societies.|
|Keywords:||Chromosome imprinting;Fertilization;DNA methyltransferase;Sequence specificity;Synthetic polymer|
|Department/Centre:||Division of Biological Sciences > Microbiology & Cell Biology|
|Date Deposited:||13 Feb 2008|
|Last Modified:||19 Sep 2010 04:42|
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