ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

X-Ray analysis of a complex of Escherichia Coli uracil DNA glycosylase(EcUDG) with a proteinaceous inhibitor. The structure elucidation of a prokaryotic UDG.

Ravishankar, R and Sagar, Bidya M and Roy, S and Purnapatre, K and Handa, P and Varshney, U and Vijayan, M (1998) X-Ray analysis of a complex of Escherichia Coli uracil DNA glycosylase(EcUDG) with a proteinaceous inhibitor. The structure elucidation of a prokaryotic UDG. In: Nucleic Acids Research, 26 (21). pp. 4880-4887.

[img] PDF
176.pdf
Restricted to Registered users only

Download (241Kb) | Request a copy

Abstract

Uracil-DNA glycosynase(UDG), a highly conserved repair enzyme involved in uracil excision repair, was diacovered in Escherichia Coli. The Bacillus subtillis bacteriophage, PBS-1 and PBS-2 which contain dump residues in their DNA, express a UDG inhibitor protein, Ugi which binds to UDG very tightly to form a physiologically irreversible complex.

Item Type: Journal Article
Additional Information: The copyright belongs to Oxford University Press
Keywords: x ray analysis;escherichia coli;dna glycosylase;uracil
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 25 Aug 2004
Last Modified: 19 Sep 2010 04:14
URI: http://eprints.iisc.ernet.in/id/eprint/1330

Actions (login required)

View Item View Item