Brahmachari, Vani and Ramakrishnan, T (1984) Modified bases in transfer RNA. In: Journal of Biosciences, 6 (5). pp. 757-770.
Transfer RNA is uniquely enriched with modified bases. A large body of information has accumulated about the occurrence, nature and distribution of modified bases in tRNA. But similar investigations on the enzymes involved in this post-transcriptional modification have been hampered by the instability of the enzymes and lack of suitable substrates. The present review summarises briefly, the occurrence and methods of detection of modified bases, the enzymes involved in their formation and also certain suggestive evidence for the role of modification in cellular metabolism.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Indian Academy of Sciences.|
|Keywords:||tRNA;methyltransferases;methylation base modification;function|
|Department/Centre:||Division of Biological Sciences > Microbiology & Cell Biology|
|Date Deposited:||24 Mar 2008|
|Last Modified:||19 Sep 2010 04:43|
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