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Evaluation of carcinogenicity of fenaminosulf (p-dimethylaminobenzenediazosodium sulfonate) and dimethyl-p-phenylenediamine in rats

Pai, S Balakrishna and Krishnabhargava, M and Vasantharajan, VN (1983) Evaluation of carcinogenicity of fenaminosulf (p-dimethylaminobenzenediazosodium sulfonate) and dimethyl-p-phenylenediamine in rats. In: Journal of Environmental Science and Health - Part A: Toxic/Hazardous Substances & Environmental Engineering, A18 (4). pp. 503-517.

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Abstract

The carcinogenicity of the fungicide fenaminosulf (I) [140-56-7] and one of its bacterial metabolites dimethyl-p-phenylenediamine (DMPDA) [99-98-9] was evaluated in rats. Over 17 mo, rats fed with 250 mg of the compound/kg of feed (in the presence or absence of nitrite) did not develop tumors. Phenols were detected in the urine and feces of rats receiving either I or DMPDA suggesting possible detoxification of these compounds

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Taylor and Francis Group
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 03 Apr 2008
Last Modified: 27 Aug 2008 13:18
URI: http://eprints.iisc.ernet.in/id/eprint/13563

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