Bhaduri, Tisha and Nagaraja, V (1994) DNA topoisomerase I from Mycobacterium smegmatis. In: Indian Journal of Biochemistry & Biophysics, 31 . pp. 339-343.
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Abstract
DNA topoisomerase I has been purified from Mycobacterium smegmatis to near homogeneity using different column chromatographic techniques. The enzyme activity relaxes form I DNA into form IV DNA, requiring Mg +2, but not ATP or any other cofactors for its activity. Several properties of the enzyme were found to be similar to that of the prototype enzyme, Escherichia coli topoisomerase I.
| Item Type: | Journal Article |
|---|---|
| Department/Centre: | Division of Biological Sciences > Microbiology & Cell Biology |
| Date Deposited: | 01 Sep 2004 |
| Last Modified: | 19 Sep 2010 04:14 |
| URI: | http://eprints.iisc.ernet.in/id/eprint/1361 |
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