Vijayan, M and Chandra, Nagasuma (1999) Lectins. In: Current Opinion in Structural Biology, 9 (6). pp. 707-714.
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Lectins — carbohydrate-binding proteins involved in a variety of recognition processes exhibit considerable structural diversity. Three new lectin folds and further elaborations of known folds have been described recently. Large variability in quaternary association resulting from small alterations in essentially the same tertiary structure is a property exhibited specially by legume lectins. The strategies used by lectins to generate carbohydrate specificity include the extensive use of water bridges, post-translational modification and oligomerisation. Recent results pertaining to influenza and foot-and-mouth viruses further elaborate the role of lectins in infection.
|Item Type:||Journal Article|
|Additional Information:||The copyright belongs to Elsevier Science Ltd.|
|Keywords:||Lectin structure;Protein folds;Carbohydrate specificity;Quaternary associations;Infection|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit
Division of Information Sciences > BioInformatics Centre
|Date Deposited:||30 Aug 2004|
|Last Modified:||19 Sep 2010 04:14|
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