Sampath, DS and Balaram, P (1986) Rapid procedure for the resolution of racemic gossypol. In: Journal of the Chemical Society, Chemical Communications (9). pp. 649-650.
Racemic gossypol [(±)-I] was resolved rapidly and efficiently by high-performance liq. chromatog. sepn. of the diastereoisomeric adducts of (±)-I with L-phenylalaninol on an achiral, reversed-phase, C18 column. The sepd. adducts were hydrolyzed by 2M HCl to give (+)- and (-)-I with 50-60% recovery.
|Item Type:||Journal Article|
|Additional Information:||Copyright belongs to Royal Society of Chemistry|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit|
|Date Deposited:||09 May 2008|
|Last Modified:||19 Sep 2010 04:44|
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