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Noise-tolerance analysis for detection and reconstruction of absorbing inhomogeneities with diffuse optical tomography using single- and phase-correlated dual-source schemes

Kanmani, B and Vasu, RM (2007) Noise-tolerance analysis for detection and reconstruction of absorbing inhomogeneities with diffuse optical tomography using single- and phase-correlated dual-source schemes. In: Physics in Medicine and Biology, 52 . pp. 1409-1429.

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Abstract

An iterative reconstruction procedure is used to invert intensity data from both single- and phase-correlated dual-source illuminations for absorption inhomogeneities. The Jacobian for the dual source is constructed by an algebraic addition of the Jacobians estimated for the two sources separately. By numerical simulations, it is shown that the dual-source scheme performs superior to the single-source system in regard to (i) noise tolerance in data and (ii) ability to reconstruct smaller and lower contrast objects. The quality of reconstructions from single-source data, as indicated by mean-square error at convergence, is markedly poorer compared to their dual-source counterpart, when noise in data was in excess of 2%. With fixed contrast and decreasing inhomogeneity diameter, our simulations showed that, for diameters below 7 mm, the dual-source scheme has a higher percentage contrast recovery compared to the single-source scheme. Similarly, the dual-source scheme reconstructs to a higher percentage contrast recovery from lower contrast inhomogeneity, in comparison to the single-source scheme.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Institute of Physics.
Department/Centre: Division of Physical & Mathematical Sciences > Instrumentation and Applied Physics (Formally ISU)
Date Deposited: 29 May 2008
Last Modified: 19 Sep 2010 04:45
URI: http://eprints.iisc.ernet.in/id/eprint/14082

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