Thangudu, Ratna R and Sharma, Priyanka and Srinivasan, N and Offmann, Bernard (2007) Analycys: A Database for Conservation and Conformation of Disulphide Bonds in Homologous Protein Domains. In: Proteins: Structure, Function, and Bioinformatics, 67 (2). pp. 255-261.
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Disulphide bonds in proteins are known to play diverse roles ranging from folding to structure to function. Thorough knowledge of the conservation status and structural state of the disulphide bonds will help in understanding of the differences in homologous proteins. Here we present a database for the analysis of conservation and conformation of disulphide bonds in SCOP structural families. This database has a wide range of applications including mapping of disulphide bond mutation patterns, identification of disulphide bonds important for folding and stabilization, modeling of protein tertiary structures and in protein engineering.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to John Wiley & Sons, Inc.|
|Keywords:||disulphide bonds;conservation; mutation;homologous proteins|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit|
|Date Deposited:||30 May 2008|
|Last Modified:||19 Sep 2010 04:45|
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