High-resolution solid-state carbon-13 nuclear magnetic resonance study of acetaminophen: a common analgesic drug

Jagannathan, NR (1987) High-resolution solid-state carbon-13 nuclear magnetic resonance study of acetaminophen: a common analgesic drug. In: Current Science, 56 (16). pp. 827-830.

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Abstract

Solid-state 13C-NMR spectra of acetaminophen were obtained by using proton enhancement combined with high-power decoupling and magic angle spinning. The contact time was detd. to obtain a max. signal to noise ratio. The chem. shifts obsd. were assigned to different carbons based on both conventional and nonquaternary suppression NMR spectra. In addn. there were no differences in the solid-state NMR spectra of Crocin and Tylenol tablets (com. brands of acetaminophen), except for the different binder content used in the formulation

Item Type:	Journal Article
Additional Information:	Copyright of this article belongs to Indian Academy of Sciences
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	11 Jun 2008
Last Modified:	19 Sep 2010 04:45
URI:	http://eprints.iisc.ernet.in/id/eprint/14263

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