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A novel conversion of narcotine into a macrolide

Samuel, Manoharan T and Madhava, Madyastha K (1986) A novel conversion of narcotine into a macrolide. In: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 25 (3). p. 227.

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Abstract

Narcotine (I) was quaternized with 3-bromopropanol; the resulting compound treated with aqueous KOH to give ring cleavage product II, which on lactonization with tosyl chloride and Et3N gave the 14-membered macrolide III.

Item Type: Journal Article
Additional Information: Copyright to this article belongs to Council of Scientific & Industrial Research.
Keywords: narcotine;macrolide
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 26 Jun 2008
Last Modified: 27 Aug 2008 13:31
URI: http://eprints.iisc.ernet.in/id/eprint/14698

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