Jacob, Alexander and Jacob, TM (1985) New model systems to study DNA-protein recognition mechanisms. In: FEBS Letters, 189 (1). pp. 81-84.
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dpG antibodies were fractionated on a cellulose-double-stranded DNA column. The flow-through fraction bound denatured DNA but not double-stranded DNA (dsDNA). The dpG-eluted fraction bound dsDNA preferentially. The results show that proteins can recognise dpG in DNA by different mechanisms, some involving DNA unwinding.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier.|
|Department/Centre:||Division of Biological Sciences > Biochemistry|
|Date Deposited:||08 Jul 2008|
|Last Modified:||19 Sep 2010 04:47|
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