Vaidya, JS and Gadgil, S (2008) Estimation of the proportion of patients in whom an experimental treatment is effective in a positive randomised trial, using a novel variance-guided equation. In: 6th European Breast Cancer Conference, p. 113.
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From the results of a positive randomised clinical trial, it cannot be ascertained whether the additional benefit is distributed to all patients or is limited to only a subgroup.We had a new insight: The variance in length of survival in the treated group will be same as the control group if the treatment is effective in every patient; but will be different if the treatment is effective in only a subgroup.
|Item Type:||Conference Proceedings|
|Additional Information:||Copyright of this article belongs to Elsevier.|
|Department/Centre:||Division of Physical & Mathematical Sciences > Mathematics|
|Date Deposited:||16 Jul 2008|
|Last Modified:||19 Sep 2010 04:47|
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