Estimation of the proportion of patients in whom an experimental treatment is effective in a positive randomised trial, using a novel variance-guided equation

Vaidya, JS and Gadgil, S (2008) Estimation of the proportion of patients in whom an experimental treatment is effective in a positive randomised trial, using a novel variance-guided equation. In: 6th European Breast Cancer Conference, p. 113.

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Abstract

From the results of a positive randomised clinical trial, it cannot be ascertained whether the additional benefit is distributed to all patients or is limited to only a subgroup.We had a new insight: The variance in length of survival in the treated group will be same as the control group if the treatment is effective in every patient; but will be different if the treatment is effective in only a subgroup.

Item Type:	Conference Proceedings
Additional Information:	Copyright of this article belongs to Elsevier.
Department/Centre:	Division of Physical & Mathematical Sciences > Mathematics
Date Deposited:	16 Jul 2008
Last Modified:	19 Sep 2010 04:47
URI:	http://eprints.iisc.ernet.in/id/eprint/14954

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