Enantioselective total synthesis of the novel antiproliferative metabolite (+)-hexacyclinol

Mehta, Goverdhan and Roy, Subhrangsu (2008) Enantioselective total synthesis of the novel antiproliferative metabolite (+)-hexacyclinol. In: Tetrahedron Letters, 49 (9). pp. 1458-1460.

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Abstract

An enantioselective total synthesis of the novel bioactive epoxyquinone natural product (+)-hexacyclinol, exhibiting promising growth inhibiting activity against cancer cell lines, has been accomplished from a readily available chiron derived from the Diels–Alder adduct of cyclopentadiene and p-benzoquinone.

Item Type:	Journal Article
Additional Information:	Copyright of this article belongs to Elsevier.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	14 Oct 2008 10:16
Last Modified:	19 Sep 2010 04:50
URI:	http://eprints.iisc.ernet.in/id/eprint/16006

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