Chopra, Deepak and Nagarajan, K and Row, Guru TN (2008) Analysis of weak interactions involving organic fluorine: Insights from packing features in substituted 4-keto-tetrahydroindoles. In: Journal of Molecular Structure, 888 (1-3). pp. 70-83.
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The role of ``organic fluorine'' in controlling the packing motifs in crystal structures which possess both strong and weak intra- and intermolecular interactions reveal that C-H center dot center dot center dot F hydrogen bonded networks provide additional stability. In this context, the crystal structures of seven new compounds have been investigated based on the molecular motif 1,5,6,7-tetrahydro-4H-indol-4-one with 4-fluorophenyl substitutions at the ``para'' position on the I-phenyl ring in four compounds and different substituents on the five-membered ring in the remaining three compounds. The features of conformational changes and the flexibility in packing based on C-H... 0, C-H center dot center dot center dot pi and C-H center dot center dot center dot F have been analyzed.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier Science.|
|Keywords:||Weak interactions;Hydrogen bonds;Organic fluorine;Molecular conformation.|
|Department/Centre:||Division of Chemical Sciences > Solid State & Structural Chemistry Unit|
|Date Deposited:||04 Dec 2008 04:49|
|Last Modified:||19 Sep 2010 04:53|
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