Mehta, Goverdhan and Singh, Robindro S (2005) Toward a total synthesis of the novel neurotrophic sesquiterpene merrilactone A: a RCM and [2+2]-photocycloaddition based approach to framework construction. In: Tetrahedron Letters, 46 (12). pp. 2079-2082.
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A new strategy toward the total synthesis of the novel structural complex and biologically potent neurotrophic factor merrilactone A from 2,3-dimethyl-2-cyclopentene-1,4-dione is outlined. The approach involving RCM and [2+2]-photocycloaddition as the key steps, is notable for the orchestration of a series of regio- and stercoselective operations that lead to the core structural motif present in the sesquiterpenoid natural product. (C) 2005 Elsevier Ltd. All rights reserved.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||09 Feb 2010 10:45|
|Last Modified:||19 Sep 2010 04:56|
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