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Irreversible genetic switch to transactivate mom gene during lytic cycle of bacteriophage Mu

Nagaraja, V (2008) Irreversible genetic switch to transactivate mom gene during lytic cycle of bacteriophage Mu. In: Indian Journal Of Virology, 19 (1). p. 55.

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Abstract

Expression of genes is regulated by ‘on’ and ‘off’ mechanisms executed at various levels. At the transcriptional level, the positive regulators (activators) turn ‘on’ gene expression while negative regulators (repressors) turn ‘off’ the expression. The genetic switches essentially achieve either induction or repression driven by the cellular requirement mediated by timely signaling events. The reversibility of the well characterized control circuits ensure optimized expression of genes. I will describe a genetic switch which appears to be irreversible.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Indian Virological Society.
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 27 Aug 2009 04:44
Last Modified: 27 Aug 2009 04:44
URI: http://eprints.iisc.ernet.in/id/eprint/17830

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