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Elucidation of the combining site of Coccinia indica agglutinin (CIA) by thermodynamic analyses of its ligand binding

Sanadi, Ashok R and Ananthram, Vellareddy and Surolia, Avadhesha (1998) Elucidation of the combining site of Coccinia indica agglutinin (CIA) by thermodynamic analyses of its ligand binding. In: Pure and Applied Chemistry, 70 (03). pp. 677-686.

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Abstract

Analyses of the ligand size dependence of the fluorescence spectra of CIA together with the thermodynamic parameters for the lectin reveal that its combining site spans the tetrasaccharide chitotetraose. Moreover the fourth sugar residue of chitoligosaccharide is proximal to a highly fluorescent tryptophan.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to International Union of Pure and Applied Chemistry.
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 03 Jun 2009 05:57
Last Modified: 19 Sep 2010 05:24
URI: http://eprints.iisc.ernet.in/id/eprint/18560

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