Prasad, Kavirayani R and Chandrakumar, Appayee (2006) Nucleophilic addition reactions of 1,4-diketones derived from tartaric acid: Synthesis of TADDOL analogues. In: Synthesis-Stuttgart (13). pp. 2159-2166.Full text not available from this repository.
A systematic investigation of the reduction and Grignard reagents addition to 1,4-diketones derived from tartaric acid was carried out. It was found that the reduction proceeded with high selectivity using K-Selectride as the reducing agent; while Grignard reagent addition was highly dependent on structure of the dione as well as on the Grignard reagent. The resultant 1,4-diols represent a series of novel TADDOL analogues.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Georg Thieme Verlag Kg.|
|Keywords:||asymmetric synthesis;TADDOL;stereoselective addition.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||06 Apr 2009 04:51|
|Last Modified:||06 Apr 2009 04:51|
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