Electronic Control of Facial Selection in Additions to Sterically Unbiased Ketones and Olefins

Mehta, Goverdhan and Chandrasekhar, Jayaraman (1999) Electronic Control of Facial Selection in Additions to Sterically Unbiased Ketones and Olefins. In: Chemical Reviews, 99 (5). pp. 1437-1467.

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Abstract

By definition, the two faces of a pi bond are equivalent.1 However, they are rendered nonequivalent in most molecules because of the absence of a plane of symmetry encompassing the double bond and the adjacent substituents. As a result, additions to trigonal centers from the two faces need not be equally facile. Exploiting this stereodifferentiation in a controlled manner represents one of the core problems in organic synthesis. Evidently, the factors which determine such diastereoselection need to be delineated in as much detail as possible.

Item Type:	Journal Article
Additional Information:	Copyright of this article belongs to American Chemical Society.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	03 Jun 2009 05:09
Last Modified:	19 Sep 2010 05:27
URI:	http://eprints.iisc.ernet.in/id/eprint/19227

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