Mehta, Goverdhan and Chandrasekhar, Jayaraman (1999) Electronic Control of Facial Selection in Additions to Sterically Unbiased Ketones and Olefins. In: Chemical Reviews, 99 (5). pp. 1437-1467.
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By definition, the two faces of a pi bond are equivalent.1 However, they are rendered nonequivalent in most molecules because of the absence of a plane of symmetry encompassing the double bond and the adjacent substituents. As a result, additions to trigonal centers from the two faces need not be equally facile. Exploiting this stereodifferentiation in a controlled manner represents one of the core problems in organic synthesis. Evidently, the factors which determine such diastereoselection need to be delineated in as much detail as possible.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to American Chemical Society.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||03 Jun 2009 05:09|
|Last Modified:||19 Sep 2010 05:27|
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