Parimoo, S and Rao, N and Padmanaban, G (1982) Cytochrome c oxidase is preferentially synthesized in the rough endoplasmic reticulum--mitochondrion complex in rat liver. In: Biochemical Journal, 208 (2). pp. 505-507.
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The specific activity and content of cytochrome oxidase in the rough endoplasmic reticulum--mitochondrion complex are higher than in the mitochondrial fraction. Radiolabelling studies with the use of hepatocytes and isolated microsomal and rough endoplasmic reticulum--mitochondrion fractions, followed by immunoprecipitation with anti-(cytochrome oxidase) antibody, reveal that the nuclear-coded cytoplasmic subunits of cytochrome oxidase are preferentially synthesized in the latter fraction. The results have a bearing on the mechanism of transport of these subunits into mitochondria.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Portland Press.|
|Department/Centre:||Division of Biological Sciences > Biochemistry|
|Date Deposited:||30 May 2009 07:18|
|Last Modified:||19 Sep 2010 05:32|
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