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Study of turbid media with light: Recovery of mechanical and optical properties from boundary measurement of intensity autocorrelation of light

Varma, Hari M and Nandakumaran, AK and Vasu, RM (2009) Study of turbid media with light: Recovery of mechanical and optical properties from boundary measurement of intensity autocorrelation of light. In: Journal of the Optical Society of America A: Optics, Image Science, and Vision, 26 (6). pp. 1472-1483.

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Abstract

We discuss the inverse problem associated with the propagation of the field autocorrelation of light through a highly scattering object like tissue. In the first part of the work, we reconstructed the optical absorption coefficient mu(u) and particle diffusion coefficient D-B from simulated measurements which are integrals of a quantity computed from the measured intensity and intensity autocorrelation g(2)(tau) at the boundary. In the second part we recover the mean square displacement (MSD) distribution of particles in an inhomogeneous object from the sampled g(2)(tau) measure on the boundary. From the MSD, we compute the storage and loss moduli distributions in the object. We have devised computationally easy methods to construct the sensitivity matrices which are used in the iterative reconstruction algorithms for recovering these parameters from the measurements. The results of the reconstruction of mu(a), D-B, MSD and the viscoelastic parameters, which are presented, show reasonable good position and quantitative accuracy.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Optical Society of America.
Department/Centre: Division of Physical & Mathematical Sciences > Mathematics
Date Deposited: 15 Dec 2009 09:17
Last Modified: 19 Sep 2010 05:38
URI: http://eprints.iisc.ernet.in/id/eprint/21644

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