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Purification, crystallization and preliminary X-ray studies of Mycobacterium tuberculosis RRF

Saikrishnan, K and Kalapala, SK and Sagar, Bidya M and Rao, AR and Varshney, U and Vijayan, M (2004) Purification, crystallization and preliminary X-ray studies of Mycobacterium tuberculosis RRF. In: Acta Crystallographica Section D, 60 . pp. 368-370.

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Abstract

With the re-emergence of tuberculosis providing the impetus, research on Mycobacterium tuberculosis at the molecular level has registered considerable progress in recent years (Ratledge & Dale, 1999). In particular, the availability of the complete genome sequence of the pathogen has facilitated such research (Cole et al., 1998). The sequence indicates the presence of about 4000 tuberculosis proteins, but the three-dimensional structures of only a few dozen of them are currently known. As part of a continuing effort in this laboratory to characterize the structures of these proteins (Datta et al., 2000, 2003; Saikrishnan et al., 2003), the crystallization and preliminary studies of the ribosome recycling factor (RRF) from this organism have been carried out.

Item Type: Journal Article
Additional Information: The copyright belongs to International Union of Crystallography.
Keywords: mycobacterium tuberculosis;crystallization;x ray studies;purification
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 16 Jan 2007
Last Modified: 19 Sep 2010 04:17
URI: http://eprints.iisc.ernet.in/id/eprint/2208

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