Majumder, Kumud and Brahmachari, Samir K and Sasisekharan, V (1986) Sequence dependence and role of 5'-phosphate in the B to Z transition. In: FEBS Letters, 198 (2). 240 -244.
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Spectroscopic studies on pd(CG)3 and pd(GC)3 have been carried out to elucidate the sequence dependence and effect of free 5'-phosphate on the B to Z transition. Unlike d(CG)3, pd(CG)3 fails to undergo salt-induced B to Z transition at ambient temperature. Model building studies have been carried out to determine the inhibitory role of the 5'-phosphate group, but have been unsuccessful.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier Science.|
|Keywords:||Sequence dependence;Deoxyoligonucleotide;B → Z transition; 5'-Phosphate effect;Circular dichroism;Ultraviolet difference spectroscopy.|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit|
|Date Deposited:||05 Feb 2010 07:29|
|Last Modified:||19 Sep 2010 05:41|
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