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Sequence dependence and role of 5'-phosphate in the B to Z transition

Majumder, Kumud and Brahmachari, Samir K and Sasisekharan, V (1986) Sequence dependence and role of 5'-phosphate in the B to Z transition. In: FEBS Letters, 198 (2). 240 -244.

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Abstract

Spectroscopic studies on pd(CG)3 and pd(GC)3 have been carried out to elucidate the sequence dependence and effect of free 5'-phosphate on the B to Z transition. Unlike d(CG)3, pd(CG)3 fails to undergo salt-induced B to Z transition at ambient temperature. Model building studies have been carried out to determine the inhibitory role of the 5'-phosphate group, but have been unsuccessful.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier Science.
Keywords: Sequence dependence;Deoxyoligonucleotide;B → Z transition; 5'-Phosphate effect;Circular dichroism;Ultraviolet difference spectroscopy.
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 05 Feb 2010 07:29
Last Modified: 19 Sep 2010 05:41
URI: http://eprints.iisc.ernet.in/id/eprint/22303

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