Chaturvedi, VK and Kurup, CK (1986) Effect of lutein on the transport of Ca2+ across phospholipid bilayer and mitochondrial membrane. In: Biochemistry International, 12 (2). 373 -377.Full text not available from this repository. (Request a copy)
Lutein (3,3'-dihydroxy alpha-carotene), a xanthophyll present in plant chloroplasts, increases the permeability of phospholipid vesicles to Ca2+, even though the pigment does not bind the metal ion. Energy-dependent uptake of Ca2+ by mitochondria is inhibited by lutein, which permits a rapid efflux of the ion from Ca2+-loaded mitochondria. These results are consistent with the view that the deleterious action of lutein on mitochondrial oxidative phosphorylation results from its destabilizing action on membrane structure.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Academic press aust.|
|Department/Centre:||Division of Biological Sciences > Biochemistry|
|Date Deposited:||31 Aug 2009 04:30|
|Last Modified:||09 Feb 2010 09:11|
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