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Effect of lutein on the transport of Ca2+ across phospholipid bilayer and mitochondrial membrane

Chaturvedi, VK and Kurup, CK (1986) Effect of lutein on the transport of Ca2+ across phospholipid bilayer and mitochondrial membrane. In: Biochemistry International, 12 (2). 373 -377.

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/3964291

Abstract

Lutein (3,3'-dihydroxy alpha-carotene), a xanthophyll present in plant chloroplasts, increases the permeability of phospholipid vesicles to Ca2+, even though the pigment does not bind the metal ion. Energy-dependent uptake of Ca2+ by mitochondria is inhibited by lutein, which permits a rapid efflux of the ion from Ca2+-loaded mitochondria. These results are consistent with the view that the deleterious action of lutein on mitochondrial oxidative phosphorylation results from its destabilizing action on membrane structure.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Academic press aust.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 31 Aug 2009 04:30
Last Modified: 09 Feb 2010 09:11
URI: http://eprints.iisc.ernet.in/id/eprint/22542

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