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Stability and structural transitions of tomato aspermy virus and cucumber mosaic virus

Savithri, HS and Devarajan, S and Murthy, MRN (1984) Stability and structural transitions of tomato aspermy virus and cucumber mosaic virus. In: Virology, 134 (2). pp. 398-405.

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Abstract

The properties of the S-strain of cucumber mosaic virus (S-CMV) and the B-strain of tomato aspermy virus (B-TAV) have been studied with respect to their (i) size and sedimentation behavior, (ii) requirement of divalent metal ions for stability, (iii) sensitivity towards chloride salts and the anionic detergent sodium dodecyl sulfate, (iv) solubility in ammonium sulfate-containing buffers, and (v) pH-dependent structural transitions. The results indicate that the coat protein of B-TAV is more hydrophobic than the other well-studied strains of TAV and CMV. Circular dichroism and uv absorption studies reveal pH-dependent structural transitions, although these do not result in particle swelling. These transitions appear to alter the strength of protein-nucleic acid interactions in these viruses.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Biological Sciences > Biochemistry
Division of Physical & Mathematical Sciences > Physics
Date Deposited: 08 Feb 2010 11:31
Last Modified: 08 Feb 2010 11:31
URI: http://eprints.iisc.ernet.in/id/eprint/22973

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