Sardana, MK and Padmanaban, G (1976) Effect of 2-allyl-2-isopropylacetamide on poly(adenylic acid)-containing ribonucleic acid. In: Biochemical Journal, 158 (2). pp. 169-174.
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A single administration of 2-allyl-2-isopropylacetamide, a porphyrinogenic drug, enhanced the 32P-labelling of nucleoplasmic as well as cytoplasmic poly(A)-containing RNA in rat liver. The synthesis of total microsomal RNA is only marginally increased under these conditions. The drug enhances the labelling of a variety of cytoplasmic poly(A)-containing RNA species, and this effect is counteracted by the simultaneous administration of haemin. 2-Allyl-2-isopropylacetamide also enhanced the release of RNA from the nucleus to the cytoplasm.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to the Biochemical Society.|
|Department/Centre:||Division of Biological Sciences > Biochemistry|
|Date Deposited:||09 Dec 2009 11:40|
|Last Modified:||19 Sep 2010 05:49|
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