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A common epitope of beta-lactoglobulin and serum retinol-binding proteins: Elucidation of its core sequence using synthetic peptides

Reddy, Kumar BMMM and Karande, Anjali A and Adiga, Radhakantha P (1992) A common epitope of beta-lactoglobulin and serum retinol-binding proteins: Elucidation of its core sequence using synthetic peptides. In: Molecular Immunology, 29 (4). pp. 511-516.

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Official URL: http://dx.doi.org/10.1016/0161-5890(92)90008-L

Abstract

One of the monoclonal antibodies raised against bovine beta-lactoglobulin reacted with human serum retinol binding protein. The finding that this monoclonal antibody also reacted with the serum retinol binding proteins isolated from other animals, suggested that this epitopic conformation is conserved among these proteins. Using ELISA and various synthetic peptides of defined sequence, we show in this paper that the epitope defined by this monoclonal antibody comprises of the highly conserved core sequence of DTDY present in beta-lactoglobulin and retinol binding proteins.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 31 Dec 2009 09:05
Last Modified: 29 Feb 2012 08:15
URI: http://eprints.iisc.ernet.in/id/eprint/24669

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