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Synthesis of leader RNA and editing of P mRNA during transcription by rinderpest virus

Ghosh, Arundhati and Nayak, R and Shaila, MS (1996) Synthesis of leader RNA and editing of P mRNA during transcription by rinderpest virus. In: Virus Research, 41 (1). pp. 69-76.

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Official URL: http://dx.doi.org/10.1016/0168-1702(95)01276-1

Abstract

Purified rinderpest virus was earlier shown to transcribe in vitro, all virus-specific mRNAs with the promoter-proximal N mRNA being the most abundant. Presently, this transcription system has been shown to synthesize full length monocistronic mRNAs comparable to those made in infected cells. Small quantities of bi- and tricistronic mRNAs are also synthesized. Rinderpest virus synthesizes in vitro, a leader RNA of not, vert, similar 55 nucleotides in length. Purified rinderpest virus also exhibits RNA editing activity during the synthesis of P mRNA as shown by primer extension analysis of the mRNA products.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier Science.
Keywords: Rinderpest virus;In vitro transcription;Leader RNA;RNA editing.
Department/Centre: Division of Biological Sciences > Molecular Reproduction, Development & Genetics (formed by the merger of DBGL and CRBME)
Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 04 Dec 2009 06:34
Last Modified: 19 Sep 2010 05:53
URI: http://eprints.iisc.ernet.in/id/eprint/25073

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