Sivapriya, Kirubakaran and Suguna, Perumal and Banerjee, Arun and Saravanan, Vadivelu and Rao, Desirazu N and Chandrasekaran, Srinivasan (2007) Facile one-pot synthesis of thio and selenourea derivatives: A new class of potent urease inhibitors. In: Bioorganic & Medicinal Chemistry Letters, 17 (22). pp. 6387-6391.
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A facile, one-pot synthesis of thio and selenourea derivatives from amines using tetrathiomolybdate 1 and tetraseleno-tungstate 2 as sulfur and selenium transfer reagents, respectively, is reported. The compounds were tested for their activity as urease inhibitors and some of the compounds showed potent activity in the nanomolar range towards jack bean urease. (C) 2007 Elsevier Ltd. All rights reserved.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Elsevier Science.|
|Department/Centre:||Division of Biological Sciences > Biochemistry
Division of Chemical Sciences > Organic Chemistry
|Date Deposited:||10 Jun 2010 06:00|
|Last Modified:||19 Sep 2010 05:57|
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