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Total Synthesis of the Novel Antifungal Agent (\pm)-Jesterone

Mehta, Goverdhan and Pan, Subhas Chandra (2004) Total Synthesis of the Novel Antifungal Agent (\pm)-Jesterone. In: Organic Letters, 6 (5). pp. 811-813.

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ol0499699


A total synthesis of the novel, biologically active epoxyquinone natural product (\pm)-jesterone has been accomplished from the readily accessible Diels-Alder adduct of cyclopentadiene and prenylated-p-benzoquinone. The approach delineated here is notable for its conceptual simplicity and efficient orchestration of a series of chemo-, regio-, and stereoselective operations.

Item Type: Journal Article
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Additional Information: Copyright for this article belongs to American Chemical Society.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 18 Jan 2005
Last Modified: 18 Jan 2012 10:09
URI: http://eprints.iisc.ernet.in/id/eprint/2653

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