Mehta, Goverdhan and Umarye, Jayant D (2001) A stereoselective total synthesis of the novel triquinane sesquiterpene cucumin E. In: Tetrahedron Letters, 42 (10). pp. 1991-1993.
A total synthesis of cucumin E, a recently isolated triquinane natural product with a new carbon framework, has been achieved. The key step is the flash vacuum pyrolysis (FVP)-induced cyclobutane fragmentation in a readily available pentacyclic caged dione to deliver the triquinane skeleton with functionalization in all the three five-membered rings suitable for further elaboration to the natural product.
|Item Type:||Journal Article|
|Additional Information:||Copyright for this article belongs to Elsevier Science.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||03 Feb 2005|
|Last Modified:||19 Sep 2010 04:17|
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