Mehta, Goverdhan and Ramesh, Senaiar S (2000) Polycyclitols. Novel conduritol and carbasugar hybrids as a new class of potent glycosidase inhibitors. In: Chemical Communications (24). pp. 2429-2430.
We have conceptualized new molecular entities (bicyclitols) in which two conduritol and two carbasugar moieties are embedded in a polyhydroxylated decahydronaphthalene framework and achieved their syntheses in a stereo- and regioselective manner. One of the bicyclitols was found to be a potent and selective \alpha-glucosidase inhibitor.
|Item Type:||Journal Article|
|Additional Information:||Copyright for this article belongs to The Royal Society of Chemistry.|
|Department/Centre:||Division of Chemical Sciences > Organic Chemistry|
|Date Deposited:||02 Feb 2005|
|Last Modified:||19 Sep 2010 04:17|
Actions (login required)