Upadhyay, Santosh Kumar and Misra, Ashish and Surolia, Namita and Surolia, Avadhesha and Sundd, Monica (2010) Backbone chemical shift assignments of the acyl-acyl carrier protein intermediates of the fatty acid biosynthesis pathway of Plasmodium falciparum. In: Biomolecular NMR Assignments .
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We report the backbone chemical shift assignments of the acyl-acyl carrier protein (ACP) intermediates of the fatty acid biosynthesis pathway of Plasmodium falciparum. The acyl-ACP intermediates butyryl (C4), -octanoyl (C8), -decanoyl (C10), -dodecanoyl (C12) and -tetradecanoyl (C14)-ACPs display marked changes in backbone HN, Cα and Cβ chemical shifts as a result of acyl chain insertion into the hydrophobic core. Chemical shift changes cast light on the mechanism of expansion of the acyl carrier protein core.
|Item Type:||Journal Article|
|Additional Information:||Copy right of this article belongs to Springer Netherlands.|
|Keywords:||Backbone assignments-Acyl-ACPs-Plasmodium falciparum - Fatty acid biosynthesis|
|Department/Centre:||Division of Biological Sciences > Molecular Biophysics Unit|
|Date Deposited:||30 Apr 2010 09:25|
|Last Modified:||19 Sep 2010 06:01|
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