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Analysis of connectivity map: Control to glutamate injured and phenobarbital treated neuronal network

Kamal, Hassan and Kanhirodan, Rajan and Srinivas, Kalyan V and Sikdar, Sujit K. (2010) Analysis of connectivity map: Control to glutamate injured and phenobarbital treated neuronal network. In: Applied Physics Letters, 96 (16).

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Official URL: http://apl.aip.org/applab/v96/i16/p163704_s1

Abstract

We study the responses of a cultured neural network when it is exposed to epileptogenesis glutamate injury causing epilepsy and subsequent treatment with phenobarbital by constructing connectivity map of neurons using correlation matrix. This study is particularly useful in understanding the pharmaceutical drug induced changes in the neuronal network properties with insights into changes at the systems biology level. (C) 2010 American Institute of Physics. [doi:10.1063/1.3398025]

Item Type: Journal Article
Additional Information: Copyright of this article belongs to American Institute of Physics.
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Division of Physical & Mathematical Sciences > Instrumentation and Applied Physics (Formally ISU)
Division of Physical & Mathematical Sciences > Physics
Date Deposited: 04 Jun 2010 05:25
Last Modified: 19 Sep 2010 06:06
URI: http://eprints.iisc.ernet.in/id/eprint/27721

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