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Use of Hydroxydiphenyl ether class of chemicals, as exemplified by Triclosan, as an antimalarial and identification of fatty acid synthesis as its target

Surolina, Namita and Kamalapriya, Dharmarajan and Ramadhani, Nagaraja Thirumala (2001) Use of Hydroxydiphenyl ether class of chemicals, as exemplified by Triclosan, as an antimalarial and identification of fatty acid synthesis as its target. Patent Number(s) WO 0100138 A2;EP 1137386 A2 . Patent Assignee(s) Indian Institute of Science;Jawaharlal Nehru Centre for Advanced Scientific Research.

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Abstract

We report the use of Hydroxydiphenyl ether class of chemicals, as exemplified by triclosan, (2,4,4,'-trichloro-2'-hydroxydiphenyl ether), for both treatment and design of therapeutics for treatment of malaria. More specifically, the present invention relates to identification of fatty acid synthesis as target for this compound as well as a key enzyme involved in synthesizing them.

Item Type: Patent
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 25 Jul 2005
Last Modified: 19 Sep 2010 04:18
URI: http://eprints.iisc.ernet.in/id/eprint/3046

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