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Role of the environment in the interaction of nonintercalators with Z-DNA

Ekambareswara, Rao and Ramesh, N and Choudhury, D and Brahmachari, SK and Sasisekharan, V (1989) Role of the environment in the interaction of nonintercalators with Z-DNA. In: Journal of Biomolecular Structure & Dynamics, 7 (2). pp. 335-345.

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/2557862

Abstract

Interaction of the DNA binding nonintercalators Netropsin, Distamycin and the mPD derivative with Z-DNA has been studied. It has been found that environmental factors like the solvent and added cations significantly modulate the interaction of these ligands with Z-DNA. However no definite Z to B transition in presence of these ligands was found in any case, in contrast to previously reported results (Ch. Zimmer, C. Marck and W. Guschlbauer, FEBS Lett. 154, 156-160 (1983)).

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Adenine Press.
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 05 Aug 2010 09:15
Last Modified: 05 Aug 2010 09:15
URI: http://eprints.iisc.ernet.in/id/eprint/31106

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