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Aggregation of calcium ionophore (A23187) in phospholipid vesicles

Balasubramanian, SV and Easwaran, KRK (1989) Aggregation of calcium ionophore (A23187) in phospholipid vesicles. In: Biochemical and Biophysical Research Communications, 158 (3). pp. 891-897.

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Official URL: http://dx.doi.org/10.1016/0006-291X(89)92806-4

Abstract

The circular dichroism studies on calcium ionophore, A23187, incorporated in Dipalmitoyl phosphatidyl choline (DPPC) vesicle showed interesting time dependent changes in the CD spectra. Analysis of the data indicated the possible aggregation of the observed dimeric structure of this molecule in non-polar solvents into a stacked dimeric pore in the phospholipid vesicle.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier science.
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 31 Aug 2010 06:12
Last Modified: 19 Sep 2010 06:15
URI: http://eprints.iisc.ernet.in/id/eprint/31572

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