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A Ca2+-sensitive cyclic-3',5'-nucleotide phosphodiesterase from sheep lung modulated by a tightly bound endogenous calmodulin.

Radhakrishnan, TS and Savithri, HS and Rao, NA and VENKITASUBRAMANIAN, TA (1988) A Ca2+-sensitive cyclic-3',5'-nucleotide phosphodiesterase from sheep lung modulated by a tightly bound endogenous calmodulin. In: Biochemistry International, 17 (5). pp. 919-925.

Full text not available from this repository.
Official URL: http://www.ncbi.nlm.nih.gov/pubmed/3151055

Abstract

Highly purified sheep lung cyclic-3',5'-nucleotide phosphodiesterase was sensitive to Ca2+/EGTA but insensitive to exogenous calmodulin. The Ca2+-sensitivity was inhibited by trifluoperazine. Heat-treated enzyme could activate a calmodulin-deficient phosphodiesterase, suggesting the presence of endogenous calmodulin in sheep lung cyclic-3',5'-nucleotide phosphodiesterase, possibly associated with the enzyme in a Ca2+-independent manner.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Academic Press Aust.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 31 Aug 2010 07:08
Last Modified: 31 Aug 2010 07:08
URI: http://eprints.iisc.ernet.in/id/eprint/31582

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