Vasantha, S and LAL, SM and Antony, A (1988) Characterization of foot-and-mouth disease virus types Ο and Asia 1 RNA. In: Journal of Biosciences, 13 (1). 39 -42.
Characterization_of_foot-and-mouth.pdf - Published Version
Foot-and-mouth disease is an acute and highly contagious febrile disease affecting cloven-footed animals. Identification of the foot-and-mouth disease virus (FMDV), the causative agent of the disease, posed problems because of the occurrence of many types and subtypes of the virus. A molecular approach based on oligonucleotide mapping of FMDV RNA has been used for the identification and characterization of virus isolates obtained in a disease outbreak (King et al., 1981). One-dimensional oligonucleotide mapping was used for rapid analysis of FMDV RNA (LaTorre et al., 1982). FMDV types Ο and Asia 1 of Indian origin are being routinely used for vaccine production in India. This report presents the differences between FMDV types Ο and Asia 1 at molecular level based on one-dimensional oligonucleotide mapping of virus-induced poly (A) RNA.
|Item Type:||Journal Article|
|Additional Information:||Copyright of this article belongs to Indian Academy of Sciences.|
|Keywords:||Foot-and-mouth disease virus;poly (A) RNA;oligo (dT)-cellulose chromatography;oligonucleotide mapping;base composition analysis.|
|Department/Centre:||Division of Biological Sciences > Microbiology & Cell Biology|
|Date Deposited:||06 Sep 2010 10:22|
|Last Modified:||19 Sep 2010 06:16|
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