ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Site of synthesis of cytochrome P-450 in liver

Bhat , Kolari S and Padmanaban, G (1978) Site of synthesis of cytochrome P-450 in liver. In: Biochemical and Biophysical Research Communications, 84 (1). pp. 1-6.

[img] PDF
site.pdf - Published Version
Restricted to Registered users only

Download (298Kb) | Request a copy
Official URL: http://dx.doi.org/10.1016/0006-291X(78)90254-1

Abstract

The suggestion that a rapidly sedimenting rough endoplasmic reticulum fraction in close association with mitochondria, is the preferred site of cytochrome P-450 synthesis has been examined. The rate of cytochrome P-450 synthesis in the different subcellular fractions has been evaluated Image , using the immunoprecipitation technique. The results indicate that the conventional microsomal fraction (100,000 X g sediment) is the major site of cytochrome P-450 synthesis and that the rapidly sedimenting rough endoplasmic reticulum fraction associated with mitochondria is not a preferred site for the hemoprotein synthesis.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 27 Sep 2010 11:39
Last Modified: 27 Sep 2010 11:39
URI: http://eprints.iisc.ernet.in/id/eprint/32460

Actions (login required)

View Item View Item